Product Name: BU63 (IgG1)
Background: CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the
Specificity: The antibody BU63 reacts with CD86 (B7-2), a 70 kDa type I transmembrane glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
Immunogen: B-lymphoblastoid cell line ARH 77
CAS NO: 1415390-47-4
Product: (R)-BPO-27
Species Reactivity: HumanOther not determined
Negative Species: Applications: Flow CytometryRecommended dilution:5 μg/mlImmunoprecipitationWestern BlottingImmunohistochemistry (frozen sections)Functional ApplicationThe antibody BU63 blocks mixed lymphocyte reaction (MLR) and binding of soluble CTLA-4 (CD152)-mulg
Applications: Flow CytometryRecommended dilution:5 μg/mlImmunoprecipitationWestern BlottingImmunohistochemistry (frozen sections)Functional ApplicationThe antibody BU63 blocks mixed lymphocyte reaction (MLR) and binding of soluble CTLA-4 (CD152)-mulg fusion protei
PubMed ID:http://aac.asm.org/content/49/8/3396.abstract

Product Name: BU63 (IgG1)
Background: CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the
Specificity: The antibody BU63 reacts with CD86 (B7-2), a 70 kDa type I transmembrane glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
Immunogen: B-lymphoblastoid cell line ARH 77
CAS NO: 934369-14-9
Product: TY-52156
Species Reactivity: HumanOther not determined
Negative Species: Applications: Flow CytometryRecommended dilution:5 μg/mlImmunoprecipitationWestern BlottingImmunohistochemistry (frozen sections)Functional ApplicationThe antibody BU63 blocks mixed lymphocyte reaction (MLR) and binding of soluble CTLA-4 (CD152)-mulg
Applications: Flow CytometryRecommended dilution:5 μg/mlImmunoprecipitationWestern BlottingImmunohistochemistry (frozen sections)Functional ApplicationThe antibody BU63 blocks mixed lymphocyte reaction (MLR) and binding of soluble CTLA-4 (CD152)-mulg fusion protei
PubMed ID:http://aac.asm.org/content/50/8/2756.abstract