Product Name: MEM-04 (IgG1)
Background: CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that m
Specificity: The antibody MEM-04 reacts with CD50 (ICAM-3), a 120-130 kDa type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells; it is negative on platelets and erythrocytes.
Immunogen: Leukocytes of a patient suffering from LGL-type leukemia.
CAS NO: 196309-76-9
Product: BAY 11-7085
Species Reactivity: Human
Negative Species: Applications: Flow CytometryRecommended dilution:5 μg/mlImmunohistochemistry (paraffin sections)Recommended dilution:10 μg/mlPositive tissue: tonsilFunctional ApplicationThe antibody MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1
Applications: Flow CytometryRecommended dilution:5 μg/mlImmunohistochemistry (paraffin sections)Recommended dilution:10 μg/mlPositive tissue: tonsilFunctional ApplicationThe antibody MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1).
PubMed ID:http://aac.asm.org/content/49/8/3404.abstract