Product Name: APC (C-terminal region)
Type: Rat Monoclonal IgG2a
Elisa: 1:1000
WB: 1:250
Background: The microtubule (MT) plus-end is a crucial site for the regulation of MT dynamics and MT association with organelles by several groups of plus-end tracking proteins (+TIPs). These +TIPs form comet-like accumulations at the plus ends of MTs to regulate MT
CAS NO.: 1257044-40-8
ABT-199
Immunogen: Clone KT45 was generated from a recombinant protein containing amino acid residues 2170 to 2394 from mouse APC. This sequence is highly conserved in human and rat APC, and has low homology to APC2.
Buffer And Storage: Rat monoclonal antibody purified with protein G chromatography is supplied in 100µl phosphate-buffered saline and 0.05% sodium azide. Aliquot and Store at –20°C. Stable for 1 year.
Specificity: This antibody detects a primarily full length APC at 300 kDa* in human Hct116 cells, mouse brain, and in rat PC12 cells. In immunocytochemistry, the antibody detects in APC in clusters at the plasma membrane and at the ends of microtubules.
PubMed ID:http://aac.asm.org/content/50/9/3160.abstract