Product Name: α-Actinin (C-terminal region)
Type: Mouse Monoclonal IgG1
Elisa: 1:2000
WB: 1:1000
Background: α-Actinins are widely expressed cytoskeletal proteins that cross-link actin filaments through anti-parallel homodimers of the rod domains. Four α-actinin genes have been discovered in humans with α-actinin 1 and 4 being widely expressed
CAS NO.: 1672665-49-4
PT-2385
Immunogen: Clone M426 was generated from a recombinant protein containing amino acids in the C-terminal region of human α-actinin 1. This sequence is well conserved in rat and mouse α-actinin 1, and is also conserved in α-actinin 2, 3, and 4.
Buffer And Storage: Mouse monoclonal antibody purified with protein A chromatography is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: The antibody detects a 100 kDa* protein corresponding to the molecular mass of α-actinins on SDS-PAGE immunoblots of human A431 and Jurkat cells, as well as rabbit spleen fibroblasts. The antibody may detect all four α-actinin family members.
PubMed ID:http://aac.asm.org/content/50/9/3011.abstract