Product Name: Atrogin-1
Type: Rat Monoclonal
Elisa: 1:2000
WB: 1:500
Background: Atrogin-1/Muscle Atrophy F-box (MAFbx) is an E3 ubiquitin ligase that mediates proteolysis events that occur during muscle atrophy. This ATP-dependent ubiquitin-mediated proteolysis occurs in response to a variety of catabolic states in muscle. Atrogin i
CAS NO.: 459789-99-2
INT-747
Immunogen: Clone M314 was generated from a synthetic peptide (coupled to carrier protein) corresponding to amino acids 23 to 35 in mouse Atrogin. This sequence is highly homologous to human and rat Atrogin (F-box only protein 32).
Buffer And Storage: Rat monoclonal, affinity-purified antibody is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: This antibody was affinity purified using Atrogin 1 peptide (without carrier). This antibody detects a full length human recombinant Atrogin 1 on SDS-PAGE immunoblots.
PubMed ID:http://aac.asm.org/content/50/10/3317.abstract