Product Name: CXCR4 (a.a. 322-329)
Type: Rabbit Polyclonal
Elisa: 1:2000
WB: 1:1000
Background: The chemokine receptor CXCR4 is a widely expressed G protein-coupled receptor required for development, hematopoiesis, organogenesis, and vascularization. In disease, CXCR4 has been implicated in WHIM syndrome, HIV, and cancers. Regulation of CXCR4 functi
CAS NO.: 195733-43-8
Atrasentan (hydrochloride)
Immunogen: CXCR4 (a.a. 322-329) synthetic peptide (coupled to carrier protein) corresponds to amino acids in the C-terminal region of human CXCR4. This sequence is conserved in mouse, rat, and chicken CXCR4, but has low homology to other CXCR family members.
Buffer And Storage: Rabbit polyclonal, affinity-purified antibody is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: The antibody detects bands at 35, 42, 50, and 100 kDa* corresponding to various post-translationally modified forms of CXCR4 on SDS-PAGE immunoblots of human Jurkat and PC3 cells. These bands co-migrate with similar bands detected with anti-CXCR4 (Ser-324
PubMed ID:http://aac.asm.org/content/50/11/3893.abstract