Product Name: FAK (Central region)
Type: Mouse Monoclonal IgG1
Elisa: 1:1000
WB: 1:250
Background: Focal adhesion kinase (FAK) is a widely expressed cytoplasmic protein tyrosine kinase involved in signal transduction pathways important for cell spreading, migration and survival. Activation of FAK by integrin clustering leads to autophosphorylation at T
CAS NO.: 1262238-11-8
INCB3344
Immunogen: Clone (M246) was generated from a recombinant protein containing amino acid in the central region of human FAK. This sequence has high homology to similar regions in rat and mouse FAK.
Buffer And Storage: Mouse monoclonal antibody purified with protein A chromatography is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: The antibody detects a 125 kDa* protein on SDS-PAGE immunoblots of human HUVEC, A431, and mouse SYF cell lysates.
PubMed ID:http://aac.asm.org/content/50/12/4161.abstract