Product Name: LIMK1 (Thr-508)[LIMK2 (Thr-505], phospho-specific
Type: Rabbit Polyclonal
Elisa: 1:2000
WB: 1:1000
Background: LIM kinases (LIMK1 and LIMK2) are serine/threonine kinases that have two zinc finger motifs, known as LIM motifs, in their amino-terminal regulatory domains. LIM kinases are involved in actin cytoskeletal regulation downstream of Rho-family GTPases, PAKs,
CAS NO.: 60940-34-3
Ebselen
Immunogen: LIMK1 (Thr-508) synthetic peptide (coupled to carrier protein) corresponding to amino acids surrounding threonine 508 in human LIMK1. This sequence is conserved in rat and mouse LIMK1, and has high homology to Thr-505 in human LIMK2.
Buffer And Storage: Rabbit polyclonal, affinity-purified antibody is supplied in 100μl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: This antibody was affinity purified using LIMK1 (Thr-508) peptide (without carrier). The antibody detects a 72 kDa* protein corresponding to the molecular mass of LIMK1 on SDS-PAGE immunoblots of activated mouse recombinant LIMK1, but does not detect this
PubMed ID:http://aac.asm.org/content/51/1/332.abstract