Product Name: MeCP2 (C-terminus)
Type: Rabbit Polyclonal
Elisa: 1:2000
WB: 1:1000
Background: Methyl-CpG Binding Protein 2 (MeCP2) was identified based on its affinity for methylated cytosines within DNA. As a chromatin-associated multifunctional protein, MeCP2 has been implicated in regulation of transcription and chromatin structure. Mutations o
CAS NO.: 256376-24-6
BAY 41-2272
Immunogen: MeCP2 synthetic peptide (coupled to KLH) corresponding to amino acid residues at the C-terminus of mouse MeCP2. This peptide sequence is highly conserved in rat and human MeCP2, and has low homology to other nuclear proteins.
Buffer And Storage: Rabbit polyclonal, affinity-purified antibody is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: This antibody was affinity purified using MeCP2 (C-terminus) peptide (without carrier). The antibody detects a 75 kDa* protein corresponding to the molecular mass of MeCP2 on SDS-PAGE immunoblots of human PC3 cells, rat PC12 cells, and mouse brain tissue.
PubMed ID:http://aac.asm.org/content/51/1/359.abstract