Product Name: PYK2 (Tyr-402), phospho-specific
Type: Mouse Monoclonal IgG1
Elisa: 1:2000
WB: 1:1000
Background: Protein tyrosine kinase, Pyk2 (CAKb, RAFTK, CADTK), is a nonreceptor tyrosine kinase structurally related to focal adhesion kinase (FAK). Pyk2 is predominantly expressed in cells derived from hematopoietic lineages and in the central nervous system. Pyk2
CAS NO.: 1032900-25-6
LDK378
Immunogen: Clone M269 was generated from a phosphopeptide containing amino acids surrounding tyrosine 402 in human PYK2. This sequence is conserved in rat and mouse PYK2, and has significant homology to the conserved site in FAK.
Buffer And Storage: Mouse monoclonal antibody purified with protein A chromatography is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: The antibody detects a 116 kDa* band corresponding to PYK2 on SDS-PAGE immunoblots of human A431, Jurkat and K562 cells treated with pervanadate, but is not observed in control, untreated cells.
PubMed ID:http://aac.asm.org/content/51/3/881.abstract