Product Name: Prion Protein (a.a. 109-112)
Type: Mouse Monoclonal IgG2a
Elisa: 1:2000
WB: 1:1000
Background: Prion related neurodegenerative diseases, called transmissible spongiform encephalopathies, are observed in many animal species. These diseases involve conversion of normal cellular prion protein (PrPc) into a form that is insoluble and resistant to prote
CAS NO.: 182004-65-5
KB-R7943 (mesylate)
Immunogen: Clone 3F4 antibody binds to amino acids 109 to 112 in human prion protein. This sequence is conserved in feline and hamster, but is less conserved in rat and mouse Prion protein.
Buffer And Storage: Mouse monoclonal antibody purified with protein A chromatography is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: The antibody detects endogenous prion protein in human PC3 and A431 cell lines. In addition, the antibody strongly detects human recombinant Prion protein, and weakly detects bovine recombinant Prion protein.
PubMed ID:http://aac.asm.org/content/51/2/748.abstract