Product Name: Smac/DIABLO (C-terminal region)
Type: Mouse Monoclonal IgG1
Elisa: 1:2000
WB: 1:1000
Background: X linked inhibitor of apoptosis (XIAP) is a member of the inhibitor of apoptosis (IAP) family of proteins, and is involved in regulating programmed cell death by caspase inhibition. SMAC/DIABLO (second mitochondria derived activator of caspase/direct IAP
CAS NO.: 374559-48-5
Istaroxime (hydrochloride)
Immunogen: Clone M359 was generated from a recombinant protein that included amino acid residues within the C-terminal region of human Smac/DIABLO. This sequence has high homology with similar regions in rat and mouse Smac/DIABLO.
Buffer And Storage: Mouse monoclonal antibody purified with protein A chromatography is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: The antibody detects a 23 kDa* band corresponding to the molecular weight of Smac/DIABLO on SDS-PAGE immunoblots of A431 cells.
PubMed ID:http://aac.asm.org/content/51/3/877.abstract