Product Name: c-Cbl (Tyr-700), phospho-specific
Type: Mouse Monoclonal IgG1
Elisa: 1:2000
WB: 1:1000
Background: c-Cbl proto-oncogene is a ubiquitously expressed cytoplasmic adaptor protein that is especially predominant in hematopoietic cells. c-Cbl possesses a highly conserved amino-terminal phosphotyrosine binding domain and a C3HC4 RING finger motif. c-Cbl is r
CAS NO.: 1234015-54-3
LY2606368 (dihydrochloride)
Immunogen: Clone (M161) was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding tyrosine 700 in human c-Cbl. This sequence is highly conserved in rat and mouse c-Cbl.
Buffer And Storage: Mouse monoclonal antibody purified with protein A chromatography is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: The antibody detects a 120 kDa* protein in human Jurkat cells treated with pervanadate, but not in control cells.
PubMed ID:http://aac.asm.org/content/50/11/3556.abstract