Product Name: mDia2 (C-terminal region)
Type: Rabbit Polyclonal
Elisa: 1:2000
WB: 1:1000
Background: Formins include several families of proteins that regulate actin cytoskeletal dynamics via two conserved formin homology domains, FH1 and FH2. The FH1 region contains poly-proline stretches that promote interactions with profilin. The FH2 domain, located
CAS NO.: 1032568-63-0
BAY 80-6946
Immunogen: mDia2 synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal region of mouse mDia2 (Diap3). This peptide sequence is highly conserved in rat and human mDia2, and has low homology to other formins.
Buffer And Storage: Rabbit polyclonal, affinity-purified antibody is supplied in 100μl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: This antibody was affinity purified using mDia2 (C-terminal region) peptide (without carrier). The antibody detects a 135 kDa* protein corresponding to the apparent molecular mass of mDia2 on SDS-PAGE immunoblots of various cells and tissues, including hu
PubMed ID:http://aac.asm.org/content/50/11/3944.abstract