Product Name: p38 MAP Kinase (Thr-180/Tyr-182), phospho-specific
Type: Mouse Monoclonal IgG1
Elisa: 1:2000
WB: 1:1000
Background: p38 MAP kinase (MAPK), also called RK, CSBP, and SAPK2a, is the mammalian orthologue of the yeast HOG kinase. This family of kinases participates in signaling cascades that control cellular responses to cytokines and stress. Four isoforms of p38 MAPK (&al
CAS NO.: 1219168-18-9
Dorsomorphin (dihydrochloride)
Immunogen: Clone M139 was generated from a phospho-p38α (Thr-180/Tyr-182) synthetic peptide (coupled to KLH) corresponding to amino acid residues around threonine 180 and tyrosine 182 of rat p38α. This peptide sequence is highly conserved in the p38&beta
Buffer And Storage: Mouse monoclonal purified with protein A chromatography is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: This antibody detects a 38 kDa* protein corresponding to the apparent molecular mass of p38α on SDS-PAGE immunoblots of pervanadate treated human Jurkat and A431 cells, as well as anisomycin treated human HeLa cells.
PubMed ID:http://aac.asm.org/content/51/2/732.abstract