Mal-PEG1-bromide

Description:
Mal-PEG1-bromide is a PEG (polyethylene glycol) bromide compound that is commonly used in bioconjugation and pegylation processes. It is a heterobifunctional PEG linker, meaning it has two different functional groups at each end – a maleimide group and a bromo group. This allows for the selective modification of biomolecules by attaching them to the PEG chain. The bromo group in Mal-PEG1-bromide provides halogenation capabilities, making it ideal for cross-linking or coupling reactions with other molecules. The maleimide group, on the other hand, reacts specifically with thiol groups on proteins, peptides, or other sulfhydryl-containing molecules. By utilizing Mal-PEG1-bromide in pegylation processes, researchers can enhance the stability and solubility of biomolecules, improve their pharmacokinetics and biodistribution, and reduce immunogenicity. This versatile compound has become an essential tool in