Name :
FITC-Labeled Human CLEC12A / MICL / CLL-1 Protein, His Tag
Background :
CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
Biological Activity :
Species :
Source :
FITC-Labeled Human CLEC12A, His Tag (CLA-HF247) is expressed from human 293 cells (HEK293). It contains AA His 65 – Ala 265 (Accession # Q5QGZ9-2). It is the FITC labeled form of Human CLEC12A, His Tag (CLA-H5245).
Tag :
Synonyms :
（Synonym）CLEC12A,MICL,CLL-1,CLL1,DCAL2,DCAL-2,CD371
Purity :
（Purity）>90% as determined by SDS-PAGE.
Storage and Stability :
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin Level :
（Endotoxin）Less than 1.0 EU per μg by the LAL method.
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 . Normally trehalose is added as protectant before lyophilization.
Protein Structure :
Refactoring Approach :
Please see Certificate of Analysis for specific instructions.
Protein Labeling :
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