So we can conclude the immediate interaction among GRP78 and cytoplasmic sCLU. nCLU lacking the chief peptide would not enter the endoplasmic reticulum, mainly localizing in the nucleus. GRP78 is largely residing in the ER. So we speculated that only cytoplasmic sCLU

All these information have been from a representative experiment and the representative consequence was from at the very least 3 independent experiments. doi:10.1371/journal.pone.0055981.g003 Western blot results corroborated the immunohistochemical staining…