Product Name: RhoA (Ser-188), phospho-specific
Type: Rabbit Polyclonal
Elisa: 1:2000
WB: 1:1000
Background: Rho (A, B, & C) proteins are members of the Ras superfamily of GTPases. These proteins regulate a variety of cellular functions, including cell cycle progression, cytoskeletal rearrangement, and gene expression. Rho cycles between the active GTP-bound
CAS NO.: 1001350-96-4
BMS-754807
Immunogen: Phospho-RhoA (Ser-188) synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 188 of human RhoA. This peptide sequence is highly conserved in rat, mouse, and chicken RhoA, but is not found in RhoB or RhoC proteins.
Buffer And Storage: Rabbit polyclonal, affinity-purified antibody is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: This antibody was affinity purified using phospho-Rho (Ser-188) peptide (without carrier). The antibody detects a RhoA GST fusion protein when phosphorylated with PKA, but does not detect the unphosphorylated recombinant protein.
PubMed ID:http://aac.asm.org/content/51/3/912.abstract