Product Name: Sphingosine Kinase 1 (C-terminal region)
Type: Rat Monoclonal
Elisa: 1:1000
WB: 1:250
Background: Sphingolipids are metabolized into bioactive products that include ceramide, sphingosine, and sphingosine-1-phosphate (S1P). Sphingosine Kinase (SK) catalyzes the phosphorylation of the lipid sphingosine, creating S1P. S1P subsequently signals through cel
CAS NO.: 1416258-16-6
(±)-BI-D
Immunogen: Clone M540 was generated from a SK1 synthetic peptide (coupled to carrier) corresponding to amino acids in the C-terminal region of mouse SK1. This sequence has high homology to human and rat SK1, and is not homologous to sequences in SK2.
Buffer And Storage: Rat monoclonal, affinity-purified antibody is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: This antibody was affinity purified using SK1 (C-terminal Region) peptide. The purified antibody detects 42 kDa* full-length recombinant human and mouse SK1 proteins, as well as detects 42, 50, and 60 kDa forms of SK1 in human HeLa cells.
PubMed ID:http://aac.asm.org/content/51/3/1078.abstract