Product Name: Sphingosine Kinase 2 (Thr-578), phospho-specific
Type: Rabbit Polyclonal
Elisa: 1:2000
WB: 1:1000
Background: Sphingolipids are metabolized into bioactive products that include ceramide, sphingosine, and sphingosine-1-phosphate (S1P). Sphingosine Kinase (SK) catalyzes the phosphorylation of the lipid sphingosine, creating S1P. S1P subsequently signals through cel
CAS NO.: 1446321-46-5
GBT 440
Immunogen: Phospho-SK2 (Thr-578) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Thr-578 in human SK2. This peptide sequence is highly conserved in rat and mouse SK2 proteins, and is not well conserved in SK1.
Buffer And Storage: Rabbit polyclonal, affinity-purified antibody is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: This antibody was affinity purified using phospho-SK2 (Thr-578) peptide (without carrier). The antibody detects 70 kDa* proteins corresponding to the molecular mass of SK2 on SDS-PAGE immunoblots of human recombinant SK2 and endogenous SK2 in human HeLa c
PubMed ID:http://aac.asm.org/content/51/3/1028.abstract