Product Name: Trop-2/TACSTD2 (Extracellular region) M005
Type: Mouse Monoclonal IgG1
Elisa: 1:2000
WB: 1:1000
Background: Trop-2 (TACSTD2) is a transmembrane glycoprotein found on invasive trophoblast cells and in several epithelial type cancer cells. Trop-2 has an extracellular domain with EGF thyroglobulin type-1 repeats, a transmembrane domain and a short cytoplasmic tail
CAS NO.: 314045-39-1
BPTES
Immunogen: Clone M005 was generated from a proprietary antigen related to the extracellular region of human Trop-2 protein.
Buffer And Storage: Mouse monoclonal antibody purified with protein G chromatography is supplied in 100 µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: Clone M005 detects a 50-65 kDa* band corresponding to the molecular mass of Trop-2 on SDS-PAGE immunoblots of native human A431, MDA-MB-231, and MCF-7 cell lysates. The antibody also detects denatured Trop-2, but with less affinity. Lower dilutions of the
PubMed ID:http://aac.asm.org/content/51/4/1487.abstract