Product Name: Yes (N-terminal region)
Type: Mouse Monoclonal IgG1
Elisa: 1:2000
WB: 1:1000
Background: c-Src was the first proto-oncogenic non-receptor tyrosine kinase characterized in human. The Src family is composed of nine members in vertebrates, including c-Src, Yes, Fgr, Yrk, Fyn, Lyn, Hck, Lck, and Blk. Src-family kinases transduce signals that are
CAS NO.: 1315329-43-1
HG6-64-1
Immunogen: Clone (M250) was generated from a recombinant protein containing amino acids in the N-terminal region of mouse Yes. This sequence has high homology to similar regions in rat and human Yes, but low homology to similar regions in other Src kinases.
Buffer And Storage: Mouse monoclonal antibody purified with protein A chromatography is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: The antibody detects a 59 kDa* protein corresponding to Yes on SDS-PAGE immunoblots of human A431 and Jurkat cells, as well as mouse brain. The antibody does not detect c-Src in mouse SYF cells transformed with c-Src.
PubMed ID:http://aac.asm.org/content/51/4/1310.abstract