Orth noting that the relative abundance of Rikenellaceae household and Tannerellaceae family members in the gut microbiota of each fecal sample was as well low (relative abundance 0.01 ) and might not be able to participate in the regulation of physiological functions. Hence, these outcomes indicated that Bacteroidetes phylum, Bacteroidia class, Bacteroidales order, Bacteroidaceae household, and Bacteroides, Alloprevotella, and Parabacteroides genus may well be closely linked with alcohol and mostly participated within the initiation and improvement of AFLD. Similarly, several other studies have identified that alcohol exposure drastically improved the relative abundance of Bacteroidetes [13,60]. Additionally, consistent with our study, a previous study reported that the abundance of Bacteroides was substantially improved in alcoholic hepatitis mice [53]. The Bacteroidetes phylum is composed of three big sorts of gram-negative bacteria, which have both valuable and dangerous traits. An animal study reported that Bacteroides fragilis could attenuate colitis by generating polysaccharide A [61]. Around the contrary, Bacteroides could also induce a pro-carcinogenic impact through creating toxins [62]. This indicated that the intestinal symbiotic bacteria were not certainly advantageous or harmful. Hence, relative analysis targeting distinct bacteria is required to clarify their influences inside the pathogenesis of AFLD.Foods 2021, 10, x FOR PEER REVIEW15 ofFoods 2021, 10,15 ofFigure eight. Cont.Foods 2021, 10,Foods 2021, ten, x FOR PEER REVIEW16 of16 ofFigure eight. The effects in the composition of microbiota in in mice impacted by chronic alcohol exposure. CTRL, the handle group; EtOH, the model BT1, Dianhong Tea; BT2, Figure eight. The effects of teas on teas on the composition of microbiotamice impacted by chronic alcohol exposure. CTRL, the control group; EtOH, the model group;group; BT1, Dianhong Tea; BT2, Yingde Black Tea; OT1, Tieguanyin Tea; OT2, Fenghuang TLR7 Inhibitor Formulation Danzong Tea; DT1, Fu Brick Tea; DT2, Selenium-Enriched Dark Tea. (A) Relative abundance of the NMDA Receptor Activator Storage & Stability faecal microbial profile of Yingde Black Tea; OT1, Tieguanyin Tea; OT2, Fenghuang Danzong Tea; DT1, Fu Brick Tea; DT2, Selenium-Enriched Dark Tea. (A) Relative abundance with the faecal microbial profile of every single group at the phylum level. (B) Relative abundance on the faecal microbial profile of each group in the genus level. (C) Relative abundance of Firmicutes, Bacteroidetes, the ratio of each group at the phylum level. (B) Relative abundance of your faecal microbial profileActinobacteria. (D) the genus level. (C) Relative abundance of Firmicutes, Bacteroidetes, the ratio of Firmicutes/Bacteroidetes, Verrucomicrobia, Proteobacteria, Epsilonbacteraeota, and of every group at Relative abundance of Ruminococcaceae_UCG-013, Akkermansia, FaecalibacuFirmicutes/Bacteroidetes, Verrucomicrobia, Proteobacteria, Epsilonbacteraeota, andpActinobacteria. (D)the model abundance of Ruminococcaceae_UCG-013, Akkermansia, Faecalibaculum, lum, Alloprevotella, Bacteroides, Parabacteroides, and Dubosiella. p 0.05, 0.01, p 0.001, Relative group compared with all the manage group; # p 0.05, ## p 0.01, ### p 0.001, the tea extract supplementary groups compared together with the model group. Alloprevotella, Bacteroides, Parabacteroides, and Dubosiella. p 0.05, p 0.01, p 0.001, the model group compared with all the handle group; # p 0.05, ## p 0.01, ### p 0.001, the tea extract supplementary groups compared with all the model group.Foods 2021, ten,17.