Tement: Not applicable. Data Availability Statement: The datasets generated for this study are offered on request to the corresponding author. Acknowledgments: This study was supported by the National Key R D Program of China (2018YFD0901006). Conflicts of Interest: The authors declare no conflict of interest.Foods 2021, 10,13 offoodsArticleChemical Content material of 5 Molluscan Bivalve Species Collected from South Korea: Multivariate Study and Security EvaluationJelena Muti1,two , Vesna Jovanovi1,two , Liesbeth Jacxsens 3 , Jannes Tondeleir three , Petar Ristivojevi1,two , c c c Sladjana Djurdji1 , Andreja Rajkovi3 and Tanja CirkoviVeli kovi1,2,three,4, c c c c cFaculty of Chemistry, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia; [email protected] (J.M.); [email protected] (V.J.); [email protected] (P.R.); [email protected] (S.D.) Division of Molecular Biotechnology, Environmental Technologies and Meals Technologies, Ghent University Global Campus, Incheon 21985, Korea Division of Food Technology, Security and Overall health, Faculty of BioScience Engineering, Ghent University, B-9000 Ghent, Belgium; [email protected] (L.J.); [email protected] (J.T.); [email protected] (A.R.) Department of Chemical and Biological Sciences, Serbian Academy of Sciences and Arts, 11000 Belgrade, Serbia Correspondence: [email protected]; Tel.: 82-32-626-4211; Fax: 82-32-626-Citation: Muti, J.; Jovanovi, V.; c c Jacxsens, L.; Tondeleir, J.; Ristivojevi, c P.; Djurdji, S.; Rajkovi, A.; c c Veli kovi, T.C. Chemical Content material of c c 5 Molluscan Bivalve Species Collected from South Korea: Multivariate Study and Safety Evaluation. Foods 2021, 10, 2690. ten.3390/ foods10112690 Academic Editor: Ewen C. D. Todd Received: 20 September 2021 Accepted: 26 October 2021 QO 58 web Published: three NovemberAbstract: Bivalves are an excellent source of nutrients but in addition a potential source of environmental contaminants, which could pose a threat for customers. The aims of this study have been: the determination of 16 elements by ICP-MS in 48 samples of 5 bivalve species 17-Hydroxyventuricidin A site purchased from industry in Korea; the identification of components valuable for species classification using multivariate analyses; plus the benefit-risk evaluation related for the consumption of these bivalves. The highest difference among content of components between species was found for Cd, Mn, Ni, Zn, and Fe. Partial last squares discriminant analysis revealed components using a VIP score 1 which were deemed because the most relevant for explaining certain species. As, Cd, Co, and Ni had been identified as taxonomical markers of V. philippinarum; Mn, Zn, Mg, and Na of A. irradians; and Cd, Ni, and Fe of M. yessoensis. These species could serve as excellent dietary sources of essential components. Cd exposure by consumption of Manila clams will not be representing a overall health risk for the Korean population; on the other hand, by way of consumption of Yesso scallops, five.3 with the Korean population includes a potential overall health threat. Removal with the digestive gland prior to consuming will drastically minimize the quantity of Cd ingested. Keywords: scallop; clam; multivariate evaluation; metal exposure assessment; ICP MS1. Introduction Bivalves have high nutritional value, and they may be considered an excellent source of proteins, lipids, and minerals [1]. Beside nutrients, bivalves could be a prospective supply of environmental organic and inorganic contaminants because they belong towards the filter feeder group of animals, which possess a tendency to accumulate.