Product Name: APA1/1 (IgG1)
Background: CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD
Specificity: The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T
Immunogen: Purified human CD3 proteins isolated from thymus
CAS NO: 920014-72-8
Product: Setmelanotide
Species Reactivity: HumanMouse
Negative Species: Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. o
Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. on ice. Wash w
PubMed ID:http://aac.asm.org/content/49/6/2554.abstract
Product Name: APA1/1 (IgG1)
Background: CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD
Specificity: The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T
Immunogen: Purified human CD3 proteins isolated from thymus
CAS NO: 920014-72-8
Product: Setmelanotide
Species Reactivity: HumanMouse
Negative Species: Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. o
Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. on ice. Wash w
PubMed ID:http://aac.asm.org/content/49/6/2554.abstract
Product Name: APA1/1 (IgG1)
Background: CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD
Specificity: The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T
Immunogen: Purified human CD3 proteins isolated from thymus
CAS NO: 920014-72-8
Product: Setmelanotide
Species Reactivity: HumanMouse
Negative Species: Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. o
Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. on ice. Wash w
PubMed ID:http://aac.asm.org/content/49/6/2554.abstract
Product Name: APA1/1 (IgG1)
Background: CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD
Specificity: The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T
Immunogen: Purified human CD3 proteins isolated from thymus
CAS NO: 920014-72-8
Product: Setmelanotide
Species Reactivity: HumanMouse
Negative Species: Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. o
Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. on ice. Wash w
PubMed ID:http://aac.asm.org/content/49/6/2554.abstract
Product Name: APA1/1 (IgG1)
Background: CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD
Specificity: The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T
Immunogen: Purified human CD3 proteins isolated from thymus
CAS NO: 920014-72-8
Product: Setmelanotide
Species Reactivity: HumanMouse
Negative Species: Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. o
Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. on ice. Wash w
PubMed ID:http://aac.asm.org/content/49/6/2554.abstract
Product Name: APA1/1 (IgG1)
Background: CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD
Specificity: The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T
Immunogen: Purified human CD3 proteins isolated from thymus
CAS NO: 1123837-84-2
Product: Sitravatinib
Species Reactivity: HumanMouse
Negative Species: Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. o
Applications: Flow CytometryPositive control: Human T cells stimulated with anti-CD3 (MEM-57) antibody (1 μg/ml)Sample preparation:At the end of stimulation of T cells, perform staining of surface markers (if required) in PBS + 0.1% BSA for 20 min. on ice. Wash w
PubMed ID:http://aac.asm.org/content/50/6/2098.abstract