Product Name: UIC2 (IgG2a)
Background: CD243, also known as multidrug resistant protein 1 (MDR-1) or P-glycoprotein (Pgp) is an ATP binding cassette (ABC)-containing efflux transporter for xenobiotic lipophilic compounds with broad substrate specificity. It is responsible for decreased drug ac
Specificity: The mouse monoclonal antibody UIC2 recognizes an extracellular epitope on CD243 (MDR-1), an approximately 170 kDa ABC transporter expressed on hematopoietic stem cells, B, T, and NK cells, or on many multidrug resistant cancer cells. This antibody prefere
Immunogen: NIH 3T3 cells transfected with human CD243 (MDR-1) cDNA
CAS NO: 113-52-0
Product: Imipramine (hydrochloride)
Species Reactivity: Human
Negative Species: MouseRat
Applications: Flow CytometryImmunoprecipitationImmunohistochemistry (paraffin sections)Application note: heat mediated antigen retrieval in citrate buffer pH 6Immunohistochemistry (frozen sections)Functional Applicationinhibition
PubMed ID:http://aac.asm.org/content/49/9/3919.abstract

Product Name: UIC2 (IgG2a)
Background: CD243, also known as multidrug resistant protein 1 (MDR-1) or P-glycoprotein (Pgp) is an ATP binding cassette (ABC)-containing efflux transporter for xenobiotic lipophilic compounds with broad substrate specificity. It is responsible for decreased drug ac
Specificity: The mouse monoclonal antibody UIC2 recognizes an extracellular epitope on CD243 (MDR-1), an approximately 170 kDa ABC transporter expressed on hematopoietic stem cells, B, T, and NK cells, or on many multidrug resistant cancer cells. This antibody prefere
Immunogen: NIH 3T3 cells transfected with human CD243 (MDR-1) cDNA
CAS NO: 166518-60-1
Product: Avasimibe
Species Reactivity: Human
Negative Species: MouseRat
Applications: Flow CytometryImmunoprecipitationImmunohistochemistry (paraffin sections)Application note: heat mediated antigen retrieval in citrate buffer pH 6Immunohistochemistry (frozen sections)Functional Applicationinhibition
PubMed ID:http://aac.asm.org/content/50/6/1921.abstract