Product Name: RCAN1/Dscr1 (a.a. 132-140)
Type: Rabbit Polyclonal
Elisa: 1:2000
WB: 1:1000
Background: An important element of calcium signaling pathways involves calmodulin activation of calcineurin (phosphatase PP2B), leading to dephosphorylation of transcription factors such as NFAT and MEF2. A wide variety of proteins other than calmodulin have also be
CAS NO.: 850664-21-0
GSK269962A
Immunogen: RCAN1 synthetic peptide (coupled to carrier protein) corresponds to amino acids 132 to 140 in human RCAN1S (isoform 2). This sequence is highly conserved in rat and mouse RCAN1, and this sequence is found in all four isoforms of RCAN1. In addition, this s
Buffer And Storage: Rabbit polyclonal, affinity-purified antibody is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: The antibody detects several isoforms of RCAN1 on SDS-PAGE immunoblots of mouse C2C12, rat PC12, and human Jurkat cells. The predominate isoform detected is the 38 kDa RCAN1L, but the antibody may also detect RCAN2 and RCAN3.
PubMed ID:http://aac.asm.org/content/51/3/864.abstract