Product Name: Sphingosine Kinase 1 (Central region)
Type: Rabbit Polyclonal
Elisa: 1:2000
WB: 1:1000
Background: Sphingolipids are metabolized into bioactive products that include ceramide, sphingosine, and sphingosine-1-phosphate (S1P). Sphingosine Kinase (SK) catalyzes the phosphorylation of the lipid sphingosine, creating S1P. S1P subsequently signals through cel
CAS NO.: 252917-06-9
CHIR-99021
Immunogen: SK1 synthetic peptide (coupled to carrier protein) corresponding to an unphosphorylated sequence of amino acids surrounding serine 225 in the central region of human SK1. This sequence has 4 amino acid differences from mouse and 5 from rat SK1, and is not
Buffer And Storage: Rabbit polyclonal, affinity-purified antibody is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: This antibody was affinity purified using SK1 (Central Region) peptide. The purified antibody detects a 47 kDa* full-length recombinant human SK1 protein. In mouse, the antibody detects SK1 in isolated cardiac myocytes, but not in SK1-null mice (Tao, R. e
PubMed ID:http://aac.asm.org/content/51/3/1011.abstract