Product Name: Vav2 (a.a. 309-322)
Type: Rabbit Polyclonal
Elisa: 1:2000
WB: 1:1000
Background: The Vav family of Rho-guanine nucleotide exchange factors, Vav1, Vav2, and Vav3, have central roles in transducing signals from cell surface receptors, such as integrin, growth factor and immune cell receptors to the cytoskeleton. This role includes recep
CAS NO.: 171596-29-5
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Immunogen: A synthetic peptide (coupled to KLH) corresponding to amino acid residues in the Dbl homology domain of human Vav2. This sequence has high homology with similar regions in rat and mouse Vav2, and has low homology to other Vav family members.
Buffer And Storage: Rabbit polyclonal, affinity-purified antibody is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.
Specificity: This antibody was affinity purified using Vav2 (a.a. 309-322) peptide (without carrier). The antibody detects a 100 kDa* doublet corresponding to the molecular mass of Vav2 on SDS-PAGE immunoblots of human Jurkat, HUVEC, and A431 cells.
PubMed ID:http://aac.asm.org/content/51/4/1380.abstract