Product Name: phospho-Asc (Tyr-144)
Type: Blocking Peptide
Elisa: 50 ng/well
WB:
Background: Host- and pathogen-associated cytoplasmic double-stranded DNA triggers the activation of a NALP3-independent inflammasome, which activates caspase-1, leading to maturation of pro-interleukin-1beta and inflammation. Several studies have isolated AIM2 (abse
CAS NO.: 1062243-51-9
Ro3280
Immunogen:
Buffer And Storage: Blocking Peptide is supplied in 50µl phosphate-buffered saline and 0.05% sodium azide.Store at –20°C. Stable for 1 year.
Specificity: The peptide is specifically recognized by Asc (Tyr-144), phospho-specific antibody (AP5631) in ELISA, and has been shown to block the reactivity of AP5631 in Western blot. In addition, the peptide is recommended for use in blocking AP5631 reactivity in im
PubMed ID:http://aac.asm.org/content/51/5/1865.abstract