The elimination of the carbohydrate at placement 386 with a 386N/A or 386N/G mutation resulted in reduced entry potential, but mutant 388T/A, which also eliminated carbohydrate at position 386, did not hurt viral infectivity
The infectivity was expressed as the proportion of the RLU of ADA-wt or HXB2wt.All of the obtainable V4 amino acid sequences from folks infected with HIV-one clade B with acknowledged…