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The calcaneal tendon, also referred to as Achilles tendon, may be the thickest and strongest tendon within the human physique [1].2,5-Furandicarboxylic acid Purity & Documentation Tendons are usually described as a dense fibrous connective tissue that attaches the muscle tissues to the bones.Chelerythrine supplier It can be constituted by a large density of collagen fibers in addition to a small variety of cells, what produces exceptionally high tensile forces [2].PMID:35567400 The collagen fibers are wrapped by a layer of connective tissue called endotenon that includes blood vessels, lymphatics, and nerves, to type larger structural units called fascicles, that are surrounded by another connective tissue layer, epitenon, to type the tendon [3]. The primary function on the tendons is to transfer the contractile forces generated by the muscles to the bones, generating movement. The area exactly where the tendons attach towards the bones is named bone-tendon junction or enthesis [4,5]. The entheses might be classified as fibrous or fibrocartilaginous [6]. Inside the fibrous entheses, tendons and/or ligaments attach for the shaft (diaphysis) on the lengthy bones and in the fibrocartilaginous, the attachment happens at the epiphyses in the extended or quick bones [2].PLO.