Product Name: HIP1 (IgG1)
Background: CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) ex
Specificity: The antibody HIP1 reacts with CD42b (GPIb alpha), a 135-145 kDa membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are composed in a disulfide linked heterodimer (CD42b/c; 160 kDa); CD42b/c forms a noncovalent com
Immunogen: Peripheral blood mononuclear cells of a patient suffering with CLL.
CAS NO: 136831-49-7
Product: RG14620
Species Reactivity: HumanNon-Human Primates
Negative Species: Applications: Flow CytometryImmunohistochemistry (frozen sections)Functional ApplicationThe antibody HIP1 inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets and ristocetin-induced platelet agglutination.
Applications: Flow CytometryImmunohistochemistry (frozen sections)Functional ApplicationThe antibody HIP1 inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets and ristocetin-induced platelet agglutination.
PubMed ID:http://aac.asm.org/content/49/7/2642.abstract
Product Name: HIP1 (IgG1)
Background: CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) ex
Specificity: The antibody HIP1 reacts with CD42b (GPIb alpha), a 135-145 kDa membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are composed in a disulfide linked heterodimer (CD42b/c; 160 kDa); CD42b/c forms a noncovalent com
Immunogen: Peripheral blood mononuclear cells of a patient suffering with CLL.
CAS NO: 548-83-4
Product: Galangin
Species Reactivity: HumanNon-Human Primates
Negative Species: Applications: Flow CytometryImmunohistochemistry (frozen sections)Functional ApplicationThe antibody HIP1 inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets and ristocetin-induced platelet agglutination.
Applications: Flow CytometryImmunohistochemistry (frozen sections)Functional ApplicationThe antibody HIP1 inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets and ristocetin-induced platelet agglutination.
PubMed ID:http://aac.asm.org/content/50/7/2300.abstract