Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This short article is distributed under the terms of the Creative Commons Attribution-NonCommercial three.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution from the function without having additional permission supplied the original operate is attributed as specified on the SAGE and Open Access pages (https://us.FT011 site sagepub.com/en-us/nam/open-access-at-sage).2 water content material, volume, or frequency of stools.11 A lower in consistency (ie, soft or liquid) and a rise in the frequency of bowel movements to three stools every day have frequently been utilised as a definition for epidemiological investigations. Depending on a community-based study perspective, diarrhea is defined as no less than 3 or more loose stools within a 24-hour period.12 A diarrheal episode is regarded as because the passage of three or extra loose or liquid stools in 24 hours prior to presentation for care, which can be viewed as the most practicable in children and adults.13 However, prolonged and persistent diarrhea can final among 7 and 13 days and at the least 14 days, respectively.14,15 The illness is extremely sensitive to climate, displaying seasonal variations in numerous web sites.16 The climate sensitivity of diarrheal illness is consistent with observations from the direct effects of climate variables around the causative ABT-737 chemical information agents. Temperature and relative humidity possess a direct influence on the price of replication of bacterial and protozoan pathogens and around the survival of enteroviruses in the atmosphere.17 Wellness care journal.pone.0169185 seeking is recognized to become a result of a complicated behavioral course of action which is influenced by quite a few factors, including socioeconomic and demographic and traits, perceived require, accessibility, and service availability.Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This short article is distributed beneath the terms of the Inventive Commons Attribution-NonCommercial three.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution of your function without having additional permission provided the original function is attributed as specified around the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).2 water content material, volume, or frequency of stools.11 A decrease in consistency (ie, soft or liquid) and a rise in the frequency of bowel movements to three stools every day have generally been used as a definition for epidemiological investigations. Depending on a community-based study perspective, diarrhea is defined as no less than 3 or much more loose stools within a 24-hour period.12 A diarrheal episode is deemed because the passage of three or more loose or liquid stools in 24 hours prior to presentation for care, which is viewed as one of the most practicable in children and adults.13 Nevertheless, prolonged and persistent diarrhea can final between 7 and 13 days and a minimum of 14 days, respectively.14,15 The illness is extremely sensitive to climate, displaying seasonal variations in various web pages.16 The climate sensitivity of diarrheal illness is constant with observations on the direct effects of climate variables around the causative agents. Temperature and relative humidity possess a direct influence on the price of replication of bacterial and protozoan pathogens and around the survival of enteroviruses in the atmosphere.17 Overall health care journal.pone.0169185 searching for is recognized to be a outcome of a complex behavioral procedure that may be influenced by various factors, like socioeconomic and demographic and qualities, perceived need, accessibility, and service availability.