Ected 53 French psychiatrists considered to become authorities in the use of LAI antipsychotics. The choice criteria were: Clinical activity inside the field of schizophrenia or bipolar disorder. Publication (s) or communication 
(s) of analysis function within the field of LAI antipsychotics in national or international congresses. Every professional was consulted individually for their expertise using the supplied questionnaire. A followup was established to ensure, primarily, the sending and returning of these documents. A reminder of the expert’s mission was produced. Written commitment from every professional was requested. The specialists participating within this project were not paid.Information analysisand tolerability (specially for SGA) [17,18]. Nonetheless, we maintained both these categories to facilitate the elaboration, the reading along with the understanding of this guideline.Rating scaleThe specialists had been capable to express their amount of agreement or disagreement for every query. The rules that describe, on the a single hand the agreement (or the disagreement), and alternatively the degree of convergence of your professional opinions, were predefined. Every expert answered every query using the support of a graduated scale from 0 to 9 (0 meaning a “total disagreement” or “a formal contraindication” and 9 indicating a “total agreement” or “a formal indication”) (Figure 1). This scale is derived from a variation with the “Nominal Group” system, developed by the Rand Corporation as well as the University of California in the USA (“RANDUCLA appropriateness rating method”). The scale has the benefit of getting well standardized, employed in medicine and of possessing been published [19].The answers to each query or proposition have been quantitatively analyzed (quantity of answers, median, mean, typical deviation, minimum, maximum) (Table two). First-line treatmentstrategy was defined if at the very least 50 of your answers to the question were within the zone 7 and significantly less than 20 have been inside the zone 0. The treatmentstrategy of decision was kept if a minimum of 50 in the professionals had rated it 9. Second-line treatmentstrategy was defined if less than 50 in the answers towards the query have been inside the zone 7, at the least 50 were within the cumulated zones 7 and 4, and less than 20 PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21310491 had been inside the zone 0. Third-line treatmentstrategy was defined if less than 50 on the answers for the question have been in theFigure 1 Rating scale.Llorca et al. BMC Psychiatry 2013, 13:340 http:www.biomedcentral.com1471-244X13Page four ofTable two Data S-[(1E)-1,2-dichloroethenyl]–L-cysteine supplier analysisPercentage of answers within the zones 0 20 20 20 50 1-3 50 4-6 50 7-9 50 First-line treatmentstrategy Second-line treatmentstrategy Third-line treatmentstrategy Contraindication50 and one hundred 50Results The following sections summarize the key recommendations in the guidelines immediately after data evaluation and interpretation of the final results with the survey by the scientific committee. The full database (with questions and answers) is readily available on the web-site www.afpbn.org. However, a number of examples of questions, using the experts’ answers, are presented right here to facilitate understanding of your results section.Description of the expert populationFor all other situations (-), the query was regarded as as non-consensual. The following rules have been used to conclude the analyzed therapeutic technique.cumulated zones 7 and four, and less than 20 have been inside the zone 0. Contraindication was defined if no less than 50 with the answers have been within the zone 0. For all other situations the query was regarded as as non-consensual. An instance is provided i.