Foundation, Chennai, in 1994 has made a substantial contribution in this path. Even so, only two of total kidneys for renal transplantation are procured from deceased renal SSTR2 review donors on account of several factors.[4-6] Deceased donor transplant program in our hospital started in 1998. Within this retrospective study, we highlight our expertise in promotion of this program.Supplies AND METHODSA retrospective evaluation on the records of 35 deceased donors and 44 renal transplant recipients from August 1998 to April 2011 was completed. Of those only 7 DDOT had been doneIndian Journal of Urology, Apr-Jun 2013, Vol 29, IssueSwami, et al.: Deceased donor renal transplantation: Our experiancetill 2005. Our DDOT program got accelerated from 2005 onward with cooptation of liver, cardiac, and corneal transplant system and also a devoted transplant coordinator inside the group. Just before 2010, among the two retrieved kidneys was shared with another institute inside the very same city. Right after 2010, we are working with both in the retrieved kidneys in our institute. All recipients had been investigated for ESRD by the nephrologists in the Division of Nephrology and had been then jointly evaluated by the integrated nephrology/urology team of your renal transplant system. Our transplant plan contains expanded criteria donors (ECDs) for renal transplantation. ECDs have been defined as per the United Network for Organ Sharing (UNOS). All donors older than 60 years or donors involving 50 and 59 years with any two from the following have been included: Hypertension, cerebrovascular trigger of brain death, or preretrieval serum creatinine (SCr) 1.5 mg/dl.[7-9] All donors and recipients had been ABO compatible, and all recipients had a unfavorable donor T-cell cross-match. The donors have been optimized in the ICU under the supervision of an intensivist. Organs had been harvested on availability and preserved with cold histidine-tryptophan ketoglutarate (HTK) remedy. Transplantation was carried out as per normal techniques. We routinely use DJ stent in our patients. All recipients received sequential triple drug immunosuppression and induction with rabbit antithymocyte globulin (rATG). Calcineurin inhibitors have been started on engraftment. Induction was commenced with steroid and rATG at a dose of 1.5 mg/kg. The very first dose of rATG was given intraoperatively and subsequent rATG infusions have been administered each day for any minimum of five and maximum of 7 doses according to initial graft function. Upkeep immunosuppression consisted of tapering doses of steroids, mycophenolate mofetil (MMF), and tacrolimus (TAC). The administration of TAC was delayed till the patient had exhibited a brisk diuresis and also a declining SCr level (4.0 mg/dl). All individuals received surgical internet site prophylaxis using a third-generation cephalosporin for 72 h, beginning just ahead of the induction of anesthesia. Delayed graft function (DGF) was defined as a failure to lower the SCr within 72 h or even a requirement for dialysis within the first week immediately after transplantation. Prolonged drainage was defined as additional than 50 ml of drainage following postoperative day 7. Postoperative complications and rejection episodes have been noted. The diagnosis of renal allograft rejection was recommended by a decline in renal function confirmed by ultrasound-guided percutaneous allograft biopsy as per the modified Banff classification.[10,11] Cellular rejections were treated with methyl prednisone (MP) 500 mg ?3-5 doses ?r-ATG 1.5 mg/kg single dose. Humoral rejections have been treated with HDAC11 Storage & Stability plasmaphere.