Its branches 1 week after the second dose in the Pfizer BioNTech COVID-19 vaccine. To the very best of our information, that is the first case report of post-COVID-19 vaccine celiac trunk vasculitis. We would like our doctor colleagues to become vigilant about such an association. Having said that, at the exact same time, we would like to emphasize that the advantages of the COVID-19 vaccine outweigh these attainable linked adverse reactions and that such temporal relation is just not authorized for causation. More analysis is needed to establish a causal relationship amongst these reactions and COVID-19 vaccines. Corresponding author. Rheumatology Section, Division of Medicine, Hamad, Healthcare Institute, Hamad General Hospital, Hamad Medical City, 3050, Doha, Qatar. E-mail address: awallaf@gmail (A.-W. Al-Allaf). Received 13 January 2022; Received in revised form 9 February 2022; Accepted 21 February 2022 Accessible on the internet 24 February 2022 2049-0801/2022 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. This really is an open access write-up below the CC BY license( Al-Allaf et al.Annals of Medicine and Surgery 75 (2022)2. Presentation of case A 46-year-old gentleman who is overweight, smoker, with no history of alcohol consumption or any considerable family members history, together with the background of well-controlled vital hypertension on amlodipine five mg day-to-day. He presented for the emergency division (ED) on March 16, 2021 having a chief complaint of epigastric and left upper quadrant abdominal pain for six days duration. The discomfort was non-radiating, extreme in intensity, rated as 7/10 as per the normalized scale ratio (NRS), stabbing in nature and didn’t respond adequately to oral analgesics including paracetamol and ibuprofen. There was no nausea, vomiting, alteration in bowel habits or urinary complaints. He had received the second dose in the Pfizer BioNTech COVID-19 vaccine a week ahead of that, on March 09, 2021, following which he knowledgeable fever and rigors for the initial day. Both doses in the vaccine were administered in the left deltoid muscle location. He worked as a driver and had not not too long ago travelled. The history was unfavorable for photosensitivity, oral ulcers, joint pain, sicca symptoms, lymphadenopathy, weight reduction and evening sweats. Within the ED, he had typical vital indicators such as oral and axillary temperature. His labs were pertinent for mildly elevated C-reactive protein of 20.3 mg/dl (reference range 0 mg/dl) but have been otherwise regular which includes adverse serum lipase and amylase. Erythrocyte sedimentation price (ESR) was 11 mm/hr (reference range 28 mm/hr). Serologic autoimmune and vasculitis panels have been adverse, which includes ANA, antiDS-DNA, Anti-RO, anti-LA, anti-SCl-70, anti-phospholipid screening, and ANCA with typical C3 and C4.IL-33 Protein medchemexpress Computed tomography (CT) scan in the abdomen with contrast revealed a fat stranding along the celiac trunk, splenic, and frequent hepatic arteries with circumferential thickened vascular walls with mural enhancement indicating inflammation suggestive of focal vasculitis (Fig.TIMP-1 Protein medchemexpress 1).PMID:23613863 In addition, confirmation using magnetic resonance imaging with the abdominal vessels wall (MRA) was obtained and revealed diffuse circumferential wall thickening with luminal narrowing and irregularity with the celiac trunk, splenic, hepatic, and left gastric arteries (Fig. 2a and b). The aorta, superior and inferior mesenteric, renal, and iliac arteries had been uninvolve.