Ymers), synthesis, and techniques of preparation, as well as formulations and biofabrication processes. Moreover, greater than 100 organizations (universities, academic institutes, businesses, foundations, government bodies, and so forth.) around the globe are at present involved in patent activity and filings regarding hydrogel-based bioinks. This trend is justified by the various positive aspects that hydrogels provide for bioprinting and biomedical applications. This can be also evident in the enhance inside the variety of patent applications filed every year worldwide in investigation and development in this location. By way of example, patent applications associated to hydrogel-based bioinks have increased from 3 to 103, throughout the period from 2013 to 2020, respectively [8]. This function within the form of patent evaluation, which is a loved ones of procedures for studying the information and facts present within and attached to patents, describes the state from the art by introducing what has been innovated and patented in relation to hydrogel-based bioinks concerning to utilized hydrogels, their preparation procedures and their formulations, at the same time Verdiperstat In stock because the 3D bioprinting method utilizing hydrogels. Furthermore, this perform gives a competitive analysis on the previous, present and future trends in the hydrogel-based bioinks and leads to various suggestions that could aid one particular to program and innovate study strategy. 2. Resources and Analysis two.1. Resources and Study Techniques The supported field codes utilised within this study have been according to the Patentscope search service of your Planet Intellectual Home Organization (WIPO) [8,9] plus the Lens patent data set [10]. Throughout the search, distinctive search phrases and connected terms were utilized, and patents have been searched as outlined by title, abstract, and claims. The search was then filtered to contain only documents with an application date till 2020.Mater. Proc. 2021, 7,three of2.2. Evaluation in the Patentability of Hydrogel-Based Bioinks The search indicates that 119 patent documents happen to be identified. Normally, it encompasses patent applications and granted patents. In relation to hydrogel-based bioinks, the identified patent documents are classed as: 103 patent applications and 16 granted patents. Here, we will assessment the state of the art by introducing what has been patented in relation to hydrogel-based bioinks. We then offer a detailed analysis on the patentability on the applied hydrogels, their preparation approaches and their formulations, as well as the 3D bioprinting process, following these sections:Publication year; Jurisdictions; Inventors; Applicants; Owners; Patent classifications.three. Final results three.1. Publication Year The date on which a patent document is published, thereby generating it a part of the state on the art. For hydrogel-based bioinks, 119 patent documents have already been located until 2020. The year 2013 saw the registration of 3 patent documents only (exclusively patent applications). Nevertheless, the year 2020 recorded 31 patent documents (24 patent applications and 7 granted patents). The maximum number of patent applications (25) was recorded in 2019. On the other hand, the maximum variety of granted patents (7) was recorded in 2020. 3.two. Jurisdictions An applicant, or first pointed out applicant in the case of joint applicants, can file an application for patent at the acceptable Patent Office (e.g., Oprozomib Autophagy European Patent Workplace (EPO), United states of america Patent and Trademark Workplace (USPTO), Korean Intellectual Home Office (KIPO), China National Intellectual House Administration (CNIPA), and so forth.) under wh.